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10 crazy prescription drug names

Appellations for medications can be a bit loopy

By  | August 20, 2013

 

1. Anakinra
Will this drug make you a sky walker? Well, if you have rheumatoid arthritis, it may help. And did the people who named this drug (brand name Kineret) have a fondness for Star Wars? It appears to be a coincidence. Interleukin receptor agonists (of which this is one) get the suffix -kinra, and if it's interleukin-1, the suffix is -nakinra. So it's just luck that if you add an a for the prefix, you get something that sounds like a young Darth Vader (now how about something for that asthma?).

2. Cisplatin
Would you put a splat right in your drug name? Well, this chemotherapy drug for cancer — a pioneer in its class, and on the market since 1978 — actually got its name from being an isomer of a platinum-containing compound. The two isomers (molecules that are the same except for their orientation) of the compound are the trans ("that side") and cis ("this side") isomers. The cis one works against some kinds of cancer.

3. Domperidone

If your stomach is not moving food through quickly and you're experiencing nausea, would you want a glass of Dom Pérignon? Hmm. How about a tablet of domperidone? It's used to treat that as well as to help nursing mothers with milk production, and is a popular choice in some places, though not officially approved in the U.S. But say… how did it get this name? All the other drugs that end in -peridone are antipsychotics. Yes, but they have this in common with domperidone: They block the effects of dopamine in your system. (Champagne, as it happens, does the opposite.)

4. Idebenone
Does this look like it should be said like "I'd be none"? Actually, it's said like "eye-deb-a-known." It's a new drug that has been tried for treating Alzheimer's disease and some other neurological disorders, but it hasn't really been very successful in the market. If you go looking for any bottles of it in your local pharmacy, I'd bet you'd find none.

5. Moxifloxacin
Two x's? This sounds like the name of a pop or rock group, but it's actually an antibiotic that you can buy under the brand name Avelox. The -floxacin signifies that it belongs to the type of drugs called fluoroquinolones. The moxi? I think the guys at Bayer who came up with the name just had some moxie — I don't think it's a double-cross.

6. Pancuronium
Does this sound like a name for a cure-all? Well, it depends on what you mean by cure, I suppose… It's a very potent muscle relaxant. That makes it useful for some surprising things. Most notably, perhaps, it's the second of three drugs given during execution by lethal injection. The cur part of the name is a reference to curare, to which it has some chemical resemblance. There are several -curonium drugs on the market. By the way, the full chemical name for pancuronium bromide is [(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-17-acetyloxy-10,13-dimethyl-2,16-bis(1-methyl-3,4,5,6-tetrahydro-2H-pyridin-1-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate. If you don't need a muscle relaxant after reading that, you're doing pretty well.

7. Phensuximide
Here we have a drug name with sux right in the middle of it. But if you think that sucks, seizures are even worse, and that's what this drug treats, though it's not a new drug and not used much anymore. It gets its name from being a succinimide, which means it's related to succinic acid — which takes its name from succinum, the Latin for "amber," which the acid can be obtained from.

8. Vinblastine
Does this drug blast away at something, maybe like some guy named Vinnie? Hmm, how about if Vinnie was with his girlfriend Christine? You see, vinblastine and the related drug vincristine are used to blast away at cancers — they're chemotherapy drugs. They get their names from Vinca rosea, which is the formal name for the Madagascar periwinkle, from which they're extracted. The blast part refers to a certain kind of precursor cell that is sometimes involved in cancers (among many other things).

9. Warfarin
Speaking of things that sound like warfare… This is actually one of the grand old drugs on the market. It's an anticoagulant drug, good for breaking up blood clots; its best-known brand is called Coumadin. It's been around longer than the U.S. Adopted Names Council, which approves generic names. Back in the 1920's, a substance found in many plants was found to cause animals to bleed to death in high enough doses. This substance was called coumarin, after coumarou, a French name for the Tonka bean. A more potent version of this substance was developed by the Wisconsin Alumni Research Foundation (WARF) and named warfarin after them. It was used as rat poison for years before it was noticed that, in appropriate doses, it could be helpful for treating humans. It's still sometimes used for warfare on rats — though still-more-potent versions are more popular now.

10. Xylometazoline
If you can't get your mouth around this, how about sticking it up your nose? I wouldn't be surprised if you already have: It's the active ingredient in Otrivin and some other decongestant nasal sprays. All drugs ending in -azoline are a particular kind of vasoconstrictor (that's not a snake, it's something that tightens up blood vessels). The xylo part happens to be a Greek root referring to wood. Which is what your nose may feel like when stuffed up.

 

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